Description
Senior Scientist – Subject Matter Expert (SME) in Mass Spectrometry
Up to £45,000 + Benefits
Full-time, On-site – Southampton
We’re partnering with an innovative scientific organisation to find an experienced Senior Scientist with deep expertise in Mass Spectrometry to join a high-performing team based in Southampton. This role offers the chance to lead analytical strategies, contribute to cutting-edge projects, and support the development of high-quality modified nucleic acid in a fast-paced, collaborative environment.
About the Role
As the subject matter expert in mass spectrometry, you’ll play a central role in driving analytical method development, ensuring high standards in nucleic acid production, and mentoring junior team members. This is a hands-on role in a modern laboratory, where scientific excellence and operational efficiency go hand-in-hand.
Key Responsibilities
- Lead and manage analytical workflows using LC-MS, UPLC-MS, HPLC, PAGE, and flash chromatography
- Act as the go-to expert for mass spectrometry, including troubleshooting and continuous improvement
- Collaborate with cross-functional teams to support small molecule preparation and oligonucleotide synthesis
- Maintain, calibrate, and optimise analytical instrumentation in line with internal and ISO quality standards
- Support and mentor Associate Scientists and Lab Technicians, providing technical guidance and training
- Ensure high levels of documentation accuracy and data integrity
- Uphold Health, Safety and Environmental (HSE) standards and promote a safety-first culture
- Manage the inventory of analytical reagents and consumables
- Stay informed on emerging techniques in nucleic acid chemistry and analytical science
About You
We’re looking for a driven and detail-focused scientist who thrives in a collaborative lab environment and is passionate about pushing the boundaries of analytical science.
You’ll ideally have:
- PhD in Chemistry, Analytical Chemistry, or a closely related field
- Significant hands-on experience with Mass Spectrometry, ideally including Waters LC-MS systems (Waters Connect experience highly desirable)
- Proven track record in high-throughput chemistry or oligonucleotide production environments
- Strong grounding in nucleic acid chemistry and experience with purification techniques
- Experience working in ISO or GMP-regulated environments
- Ability to lead projects and mentor junior staff
- Excellent communication, problem-solving and organisational skills
- A proactive mindset, able to adapt and perform under pressure
Salary & Benefits
- Salary: Up to £45,000 depending on experience
- Location: On-site in Southampton
- Holidays: 25 days annual leave + 8 bank holidays
- Pension: 6% employer contribution
- Work-Life Balance: Flexible working hours
- Life Assurance: 4x salary
- Other Benefits:
- Long service awards
- Reward and recognition scheme
- Employee Assistance Programme with 24/7 remote GP access
- Annual flu vaccinations
- Cycle to work scheme
- Gym discounts
- Discount and savings platform
- Professional membership reimbursement
- Referral incentives
- Social events and volunteering days
Want to lead innovation in mass spectrometry and oligonucleotide production?
If you're ready to make an impact in a dynamic and supportive environment, we’d love to hear from you. Apply today or get in touch to learn more.
